百济神州：港股公告：百济神州有限公司截至2023年3月31日止三个月未经审核业绩以及业务进展最新情况

BeiGene, Ltd.

06160

2023331

13.09

571XIVA

2023331

202333120232023

202354

1995(Private Securities LitigationReform Act of 1995)

?

10-K

202354

Margaret Han DuganDonald W. GlazerMichael GollerAnthony C. HooperRanjeev KrishanaThomasMalleyAlessandro RivaCorazon (Corsee) D. Sanders

2023?20234.1032.616

56.9%

?

?

(CLL)(SLL)

?

20232.114

?

??

202354BGNE06160688235

2023

(John V. Oyler)??

?BTK

?CLL

(Julia Wang)

2023

20233314.4782022

3.066

? 20233314.1032022

2.616

2023

?

2.114

1.043

2023

?

1.149

8,760 20233,640

2,990? 20233313,750

2021

?

20214,510

20238,1806,520

????

202380.1%

75.1%

??

?

20233317.37320226.847? 20233314.086

3.899

20233,400

3,090? (SG&A)2023331SG&A

3.2852.946SG&A20232022SG&A4,1403,470

20233313.484

0.26(ADS)3.342022

4.3520.33ADS4.25

20232023331382022123145? 20233315.638

3.484

2.9417,870

1.2561,99020223312.366

4.3528,090

1.177

4,5101,130

? 202357%

??

? 2023

?

2.114

103%CLL/SLL

?2023

1.388104%

?

FDA?20234,81044%? 2023

?

1.149

31%

?

?

(BTK)BTK

?

4,900? 3ALPINE

?

R/R CLL

(FDA)? CLL/SLL?

?

R/R(FL)(sNDA)R/R CLLPFS

? ACCESS(ACCESS consortium)

?

R/R FLsNDA?

?202330

?

IgG4PD-1Fcγ

?

?3112,100? 2023(AACR)RATIONALE-

302(NCT03430843)RATIONALE-304(NCT03663205)RATIONALE-306(NCT03783442)RATIONALE-307(NCT03594747)?

?

? FDA

?

(BLA)(BGB-A1217)FcTIGIT

201,700

?

?

(NSCLC)2(NCT05014815)BGB-11417BCL-2

?

B(AML)(MDS)

(MM)BGB-114177430? BGB-11417R/R(MCL)(NCT05471843)R/R

CLL/SLL(NCT05479994)2

BGB-A445OX40

?

?

?

1(NCT04215978)

?

BGB-B167CEA x 4-1BB

?

CEA(CRC) BGB-A425

?NSCLCTIM-3

BGB-15025

?

1(HPK1) BGB-16673(CDAC)BTK

B BGB-24714(SMAC)

2023AACR BGB-10188

??

PI3Kδ BGB-233392(TYK2)

? SpringWorks TherapeuticsAACRB-RAF

lifirafenib(BGB-283)SpringWorksMEKmirdametinibRASRAFMAPK1b

? MapKureSpringWorksAACRRAF

brimarafenib (BGB-3245)MAPK

1a/b? LAG-3LBL-007

?

CRC2(NCT05609370)? LBL-007

??

BGB-A445NCT05635708NCT05577702

?

1009.3

?

54,000202310,000

? (ADC)

2024

2025?

55.95.262023

?

?

? FDA(EMA)R/R CLL

??

R/R CLLPFS

? CLL/SLLWMsNDA

2023? CLLsNDA2023

?

?

? 2023ASCO

?

R/RB

?ROSEWOOD?? NMPA

?

(BLA)

ESCC20232023

?

?

(TGA)

?

NSCLCESCCBLA2023

(Medsafe)

?NSCLCESCCBLA (MFDS)

?

ESCCBLA (Anvisa)

?

NSCLCESCCBLA?

?

FDA

?

ESCCBLA2023 EMA

?

NSCLCESCC2023

?

NSCLCESCC

?

ESCCNSCLC 2023FDA

?

ESCC 2023

?ESCCBLA? 2023? 2023ASCORATIONALE 301BGB-11417BCL-2

? 2023

?

CLL?? 2023ASCO1BGB-11417

B

TIGIT

? 20232

PD-(L)1ESCC(NCT04732494) (NCT04948697) NSCLC(NCT05014815)? 2023NSCLC3AdvanTIG-302? 2023ASCO1bAdvanTIG-105

BGB-16673(BTK CDAC)

? 2023B1NCT05006716

NCT05294731BGB-A445OX40

? 20231(NCT04215978)? 2023ASCOOX40BGB-A445

?

BGB-15025HPK1

? 2023

?

(NCT04649385)

? 2023ASCOHER2

zanidatamabHER21b/2

zanidatamabHER22bHERIZON-BTC-01

202320223311231

$3,837,823$4,540,288309,628173,168296,995282,346925,404845,9465,956,7756,379,290

241,360294,781417,922467,352222,822255,887276,562293,960488,106538,1171,799,4691,995,935$4,157,306$4,383,355

ADSADS

331320232022

$410,291$261,573 37,51045,053

447,801306,626 81,78965,237 408,584389,915 328,499294,573 187188 819,059749,913

(371,258)(443,287) 16,01610,071 18,30311,967

(336,939)(421,249)

11,49213,949

(348,431)(435,198) $(0.26)$(0.33) 1,354,164,7601,332,017,262

ADS $(3.34)$(4.25)

ADS 104,166,520102,462,866

2022202333110-Q1.

2.

9,400 http://www.beigene.com.cn

1995(Private Securities LitigationReform Act of 1995)

?

10-K

(+86 10)5895-8058(+86 10)6844-5311ir@beigene.commedia@beigene.com

?????

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